A STUDY OF THE FREQUENCY AND TYPE OF MUTATION IN EXON 11 IN BRCA1 AND BRCA2 GENES IN BREAST CANCER WOMEN WITH POSITIVE FAMILY HISTORY

A study of The Frequency and Type of Mutation in Exon 11 in BRCA1 and BRCA2 Genes In Breast Cancer Women With Positive Family History

Background:Both BRCA1 and BRCA2 are tumor suppressor gene and are inherited as an autosomal dominant.The cumulative lifetime risk of developing invasive breast cancer for those with BRCA1 or BRCA2 mutations ranges from 53% to 89%.Familial breast cancer represent less than 10% of all cancers of the breast, and cancers related to BRCA1 and BRCA2 fami

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IDENTIFICATION OF SANDFLIES (Diptera: Psychodidae: Phlebotominae) BLOOD MEALS IN AN ENDEMIC LEISHMANIASIS AREA IN BRAZIL

SUMMARY The aim of this study was to identify blood meals of female sandflies captured in the municipality of Governador Valadares, an endemic area Broths of visceral and cutaneous leishmaniasis, in the State of Minas Gerais, Brazil.From May 2011 to January 2012, captures were performed using HP light traps in four districts.There were 2,614 specim

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Associations between body size, nutrition and socioeconomic position in early life and the epigenome: A systematic review.

BackgroundBody size, nutrition and socioeconomic position (SEP) in early life have been associated with a wide range of long-term health Hemorrhoidal effects.Epigenetics is one possible mechanism through which these early life exposures can impact later life health.We conducted a systematic review examining the observational evidence for the impact

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